Logo-apb
Adv Pharm Bull. 2020;10(2): 307-314. doi: 10.34172/apb.2020.037
PMID: 32373501        PMCID: PMC7191235

Research Article

Interleukin-6, -8, and TGF-β Secreted from Mesenchymal Stem Cells Show Functional Role in Reduction of Telomerase Activity of Leukemia Cell Via Wnt5a/β-Catenin and P53 Pathways

Ezzatollah Fathi 1 ORCID, Behnaz Valipour 2 ORCID, Zohreh Sanaat 3 ORCID, Hojjatollah Nozad Charoudeh 4 ORCID, Raheleh Farahzadi 3 * ORCID

Cited by CrossRef: 34


1- Abbasi B, Shamsasenjan K, Ahmadi M, Beheshti S, Saleh M. Mesenchymal stem cells and natural killer cells interaction mechanisms and potential clinical applications. Stem Cell Res Ther. 2022;13(1) [Crossref]
2- Fathi E, Vietor I. Mesenchymal Stem Cells Promote Caspase Expression in Molt-4 Leukemia Cells Via GSK-3α/Β and ERK1/2 Signaling Pathways as a Therapeutic Strategy. CGT. 2021;21(1):81 [Crossref]
3- Sarkar A, Saha S, Paul A, Maji A, Roy P, Maity T. Understanding stem cells and its pivotal role in regenerative medicine. Life Sciences. 2021;273:119270 [Crossref]
4- Ren S, Xiong H, Chen J, Yang X, Liu Y, Guo J, Jiang T, Xu Z, Yuan M, Liu Y, Zhou N, Chen H, Li W, Machens H, Chen Z. The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients. Stem Cell Res Ther. 2021;12(1) [Crossref]
5- Yang K, Pei L, Zhou S, Tao L, Zhu Y. Metformin attenuates H2O2‑induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway. Exp Ther Med. 2021;22(5) [Crossref]
6- Wei X, Li Y, Zhang G, Wang N, Mi M, Xin Y, Jiang H, Sun C. IL-37 Was Involved in Progress of Acute Myeloid Leukemia Through Regulating IL-6 Expression. CMAR. 2021;Volume 13:3393 [Crossref]
7- Muzsai S, Maryanovsky O, Ander R, Koncz G, Mázló A, Bácsi A, Tóth M. Cell-Free Supernatant Derived from a Lactobacillus casei BL23 Culture Modifies the Antiviral and Immunomodulatory Capacity of Mesenchymal Stromal Cells. Biomedicines. 2023;11(6):1521 [Crossref]
8- M, S, M, E. MSCs modifies the proliferation of leukemia MOLT-4 cells and induces their apoptosis through up-regulating Bax, caspase-3, and-8, and down-regulating Bcl-2 expression. Ann Cancer Res Therap. 2021;29(1):79 [Crossref]
9- Chu M, Wan H, Zhang X. Requirement of splicing factor hnRNP A2B1 for tumorigenesis of melanoma stem cells. Stem Cell Res Ther. 2021;12(1) [Crossref]
10- Liu S, Hou X, Zhao F, Zhao X. Nucleated red blood cells participate in myocardial regeneration in the toad Bufo Gargarizan Gargarizan. Exp Biol Med (Maywood). 2021;246(15):1760 [Crossref]
11- Oh I, Raymundo B, Jung S, Kim H, Park J, Kim C. Extremely Low‐Frequency Electromagnetic Field Altered PPARγ and CCL2 Levels and Suppressed CD44+/CD24− Breast Cancer Cells Characteristics. Bulletin Korean Chem Soc. 2020;41(8):812 [Crossref]
12- Wang X, Yang Y, Wang N, Wu X, Xu J, Zhou Y, Zhao X, He Z. Mesenchymal stem cell carriers enhance antitumor efficacy induced by oncolytic reovirus in acute myeloid leukemia. International Immunopharmacology. 2021;94:107437 [Crossref]
13- Yuan Z, Zhu Z, Zhu F, Ding F, Wang Y, Wang X, Luo X, Yang J, Liu F, Sun D. Impact of human adipose tissue-derived stem cells on dermatofibrosarcoma protuberans cells in an indirect co-culture: an in vitro study. Stem Cell Res Ther. 2021;12(1) [Crossref]
14- Fan X, Yang H, Zhao C, Hu L, Wang D, Wang R, Fang Z, Chen X. Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation. Stem Cell Res Ther. 2021;12(1) [Crossref]
15- Fathi E, Farahzadi R, Valipour B. Alginate/gelatin encapsulation promotes NK cells differentiation potential of bone marrow resident C-kit+ hematopoietic stem cells. International Journal of Biological Macromolecules. 2021;177:317 [Crossref]
16- Tsai M, Hung S, Weng C, Fan S, Liou D, Huang W, Liu K, Cheng H. Stem cell transplantation and/or adenoviral glial cell line-derived neurotrophic factor promote functional recovery in hemiparkinsonian rats. WJSC. 2021;13(1):78 [Crossref]
17- Ni H, Qin H, Sun C, Liu Y, Ruan G, Guo Q, Xi T, Xing Y, Zheng L. MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis. Stem Cell Res Ther. 2021;12(1) [Crossref]
18- Ding Z, Liu J, Qian H, Wu L, Lv M. Cinnamaldehyde inhibits psoriasis‑like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF‑κB and JNK signaling pathways. Mol Med Rep. 2021;24(3) [Crossref]
19- Li X, Li L, Wu J. The members of the miR-148/152 family inhibit cancer stem cell-like properties in gastric cancer via negative regulation of ITGA5. J Transl Med. 2023;21(1) [Crossref]
20- Qu W, Zhao J, Wu Y, Xu R, Liu S. Recombinant Adeno-associated Virus 9-mediated Expression of Kallistatin Suppresses Lung Tumor Growth in Mice. CGT. 2021;21(1):72 [Crossref]
21- Prasetyo E, Kuntjoro M, Goenharto S, Juniarti D, Cahyani F, Hendrijantini N, Nugraha A, Hariyani N, Rantam F. Calcium Hydroxide Increases Human Umbilical Cord Mesenchymal Stem Cells Expressions of Apoptotic Protease-Activating Factor-1, Caspase-3 and Caspase-9. CCIDE. 2021;Volume 13:59 [Crossref]
22- Adibkia K, Ehsani A, Jodaei A, Fathi E, Farahzadi R, Barzegar-Jalali M. Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension. Beilstein J Nanotechnol. 2021;12:786 [Crossref]
23- Zhang L, Chi Y, Wei Y, Zhang W, Wang F, Zhang L, Zou L, Song B, Zhao X, Han Z. Bone marrow-derived mesenchymal stem/stromal cells in patients with acute myeloid leukemia reveal transcriptome alterations and deficiency in cellular vitality. Stem Cell Res Ther. 2021;12(1) [Crossref]
24- Tian G, Hu K, Qiu S, Xie Y, Cao Y, Ni S, Zhang L. Exosomes derived from PC‑3 cells suppress osteoclast differentiation by downregulating miR‑148a and blocking the PI3K/AKT/mTOR pathway. Exp Ther Med. 2021;22(5) [Crossref]
25- Tufail M, Wu C. WNT5A: a double-edged sword in colorectal cancer progression. Mutation Research/Reviews in Mutation Research. 2023;792:108465 [Crossref]
26- Xiang Y, Yu Y, Li Q, Jiang Z, Li J, Liang C, Chen J, Li Y, Chen X, Cao W. Mutual regulation between chicken telomerase reverse transcriptase and the Wnt/β-catenin signalling pathway inhibits apoptosis and promotes the replication of ALV-J in LMH cells. Vet Res. 2021;52(1) [Crossref]
27- He Z, Zhuo R, Yang S, Zhou P, Xu J, Zhou J, Wu S. CircNCOR1 regulates breast cancer radiotherapy efficacy by regulating CDK2 via hsa-miR-638 binding. Cellular Signalling. 2023;109:110787 [Crossref]
28- Fathi E, Azarbad S, Farahzadi R, Javanmardi S, Vietor I. Effect of Rat Bone Marrow Derived-Mesenchymal Stem Cells on Granulocyte Differentiation of Mononuclear Cells as Preclinical Agent in Cellbased Therapy. CGT. 2022;22(2):152 [Crossref]
29- Razi Soofiyani S, Ahangari H, Soleimanian A, Babaei G, Ghasemnejad T, Safavi S, Eyvazi S, Tarhriz V. The role of circadian genes in the pathogenesis of colorectal cancer. Gene. 2021;804:145894 [Crossref]
30- Montazersaheb S, Fathi E, Farahzadi R. Cytokines and signaling pathways involved in differentiation potential of hematopoietic stem cells towards natural killer cells. Tissue and Cell. 2021;70:101501 [Crossref]
31- Hu Y, Shen X, Liu F, Zhu W. Phoenixin-14 Ameliorates Cellular Senescence Against Morphine in M17 Neuronal Cells. Neurotox Res. 2022;40(2):498 [Crossref]
32- Hong M, Guo J, Zhao Y, Song L, Zhao S, Wang R, Shi L, Zhang Z, Wu D, He Q, Chang C. Eltrombopag restores proliferative capacity and adipose-osteogenic balance of mesenchymal stromal cells in low-risk myelodysplastic syndromes. European Journal of Pharmacology. 2024;985:177086 [Crossref]
33- Li T, Luo C, Zhang J, Wei L, Sun W, Xie Q, Liu Y, Zhao Y, Xu S, Wang L. Efficacy and safety of mesenchymal stem cells co-infusion in allogeneic hematopoietic stem cell transplantation: a systematic review and meta-analysis. Stem Cell Res Ther. 2021;12(1) [Crossref]
34- Geng S, Zhu L, Wang Y, Liu Q, Yu C, Shi S, Yu S. Co-Colorectal cancer stem cells employ the FADS1/DDA axis to evade NK cell-mediated immunosuppression after co-cultured with NK cells under hypoxia. International Immunopharmacology. 2024;143:113535 [Crossref]
35- Mastelaro de Rezende M, Zenker Justo G, Julian Paredes-Gamero E, Gosens R. Wnt-5A/B Signaling in Hematopoiesis throughout Life. Cells. 2020;9(8):1801 [Crossref]