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Adv Pharm Bull. 2021;11(3): 477-489. doi: 10.34172/apb.2021.055
PMID: 34513622        PMCID: PMC8421626

Research Article

Novel Methotrexate-Ciprofloxacin Loaded Alginate-Clay Based Nanocomposite as Anticancer and Antibacterial Co-Drug Delivery System

Mehrdad Mahkam 1 ORCID, Fatemeh Bazmi Zeynabad 1, Effat Alizadeh 2, Mahdi Rahimi 3, Fariborz Rahimi 4 * ORCID, Roya Salehi 5 * ORCID

Cited by CrossRef: 6


1- Sarvari R, Naghili B, Agbolaghi S, Abbaspoor S, Bannazadeh Baghi H, Poortahmasebi V, Sadrmohammadi M, Hosseini M. Organic/polymeric antibiofilm coatings for surface modification of medical devices. International Journal of Polymeric Materials and Polymeric Biomaterials. 2023;72(11):867 [Crossref]
2- Alva-Ensastegui J, Morales-Avila E, de la Luz A, Bernad-Bernad M. Determination of pKa values and deprotonation order of methotrexate using a combined experimental-theoretical study and binding constants of the methotrexate-Laponite complex at different pH values. Journal of Photochemistry and Photobiology A: Chemistry. 2024;449:115406 [Crossref]
3- Hashim A, Abd-Rabou A, El-Sayed H. Functional nanoemulsion and nanocomposite microparticles as an anticolorectal cancer and antimicrobial agent: applied in yogurt. Biomass Conv Bioref. 2022; [Crossref]
4- Mondal A, Nayak A, Chakraborty P, Banerjee S, Nandy B. Natural Polymeric Nanobiocomposites for Anti-Cancer Drug Delivery Therapeutics: A Recent Update. Pharmaceutics. 2023;15(8):2064 [Crossref]
5- Safaee-Ardakani M, Hatamian-Zarmi A, Sadat S, Alvandi H, Ebrahimi-Hosseinzadeh B, Mokhtari-Hosseini Z, Mohammadi M. In vivo study of beta-glucan-based biogenic synthesis of silver nanocomposite using Schizophyllum commune for wound dressings in a rat burn model. Adv Nat Sci: Nanosci Nanotechnol. 2022;13(3):035001 [Crossref]
6- Shariati A, Arshadi M, Khosrojerdi M, Abedinzadeh M, Ganjalishahi M, Maleki A, Heidary M, Khoshnood S. The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic. Front Public Health. 2022;10 [Crossref]
7- Tiwari P, Nadeem M, Dua S, Rizvi M, Arfin N. Zein - laponite coacervate aided co-delivery of curcumin and cisplatin towards MDA-MB-231 breast cancer cells: Validating the concept. Food Hydrocolloids for Health. 2023;4:100164 [Crossref]
8- Farshi Azhar F, Ahmadinia A, Mousazadeh H, Kheirkhah E. A pH-sensitive magnetic hydrogel nanocomposite based on alginate for controlled release of methotrexate. International Journal of Polymeric Materials and Polymeric Biomaterials. 2023;:1 [Crossref]
9- Yao L, Liu Q, Lei Z, Sun T. Development and challenges of antimicrobial peptide delivery strategies in bacterial therapy: A review. International Journal of Biological Macromolecules. 2023;253:126819 [Crossref]
10- Mohammadpour-Haratbar A, Zare Y, Rhee K. A Review on Drug Delivery Systems Containing Polymer Nanocomposites for Breast Cancer Treatment. Polymer Reviews. 2023;:1 [Crossref]