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Adv Pharm Bull. 2020;10(4): 602-609. doi: 10.34172/apb.2020.072

PMID: 33072538 PMCID: PMC7539306

Research Article

(+)-Catechin & Proanthocyanidin Fraction of Uncaria gambir Roxb. Improve Adipocytes Differentiation & Glucose Uptake of 3T3-L1 Cells Via Sirtuin-1, Peroxisome Proliferator-Activated Receptor γ (PPAR γ), Glucose Transporter Type 4 (GLUT-4) Expressions

Silvy Arundita ¹ , Friardi Ismed ², Rauza Sukma Rita ¹, Deddi Prima Putra ² *

Cited by CrossRef: 8

1- Armenia A, Wahyuni F, Almahdy A, Abdillah R, Aquista P, Putri D, Zikra M. Blood pressure and blood sugar-lowering effects of purified gambir on diabetic hypertensive Wistar Kyoto rats. 2022;19(3):627 [Crossref]

2- Armenia A, Badriyya E, Rahmita S, Rachmaini F, Abdillah R. Malondialdehyde and TNF-α lowering effects of purified gambier (Uncaria gambir Roxb.) in diabetic rats. Journal of Ayurveda and Integrative Medicine. 2024;15(1):100855 [Crossref]

3- Rizaldi T, Indahwati C, Kurniawan I, Sinaga R. Performance Evaluation of a Mechanically Driven Screw Press for Gambir Sap Extraction. Eng Technol Appl Sci Res. 2026;16(5):38738 [Crossref]

4- RACHMAINI F, RACHMAINI A, ABDILLAH R. PURIFIED GAMBIR (UNCARIA GAMBIR (HUNTER) ROXB.) ATTENUATE RENAL FUNCTION IN ALLOXAN-INDUCED DIABETIC MALE RATS. Int J App Pharm. 2024;:160 [Crossref]

5- Abdillah R, Maulina M, Rahmatika A, Suharti N, Armenia A. Roselle Calyx (Hibiscus sabdariffa L.) Ethyl Acetate Fraction Lowering Malondialdehyde and TNF-α and Reducing Hypercoagulability in Diabetic Model. Pharmacology. 2024;109(5):243 [Crossref]

6- M, S, F, Oktabriana G, Oktabriana H, Oktabriana M, Oktabriana H, Oktabriana R. Variation in Leaf Characteristics, Production, and Catechin Content of Gambir Based on Cultivation Site and Plant Type in Mungka District, Indonesia. JRP. 2026;7(2):70 [Crossref]

7- Tachibana K, Fukuda S, Fukushima J, Ishimoto K, Sakata M, Nishimori Y, Doi T. Exploring compounds to be used as cosmetic agents that activate peroxisome proliferator‐activated receptor alpha. Intern J of Cosmetic Sci. 2022;44(2):189 [Crossref]

8- Fauziah F, Ali H, Ilmiawati C, Ariyanto E, Bakhtra D, Mita D, Syafni N, Handayani D. Non-monotonic dose-response of di-(2-ethylhexyl) phthalate isolated from Penicillium citrinum XT6 on adipogenesis and expression of PPARγ and GLUT4 in 3T3-L1 adipocytes. 2023;20(4):804 [Crossref]

9- Abral H, Ikhsan M, Rahmadiawan D, Handayani D, Sandrawati N, Sugiarti E, Muslimin A. Anti-UV, antibacterial, strong, and high thermal resistant polyvinyl alcohol/Uncaria gambir extract biocomposite film. Journal of Materials Research and Technology. 2022;17:2193 [Crossref]