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Adv Pharm Bull. 2021;11(1): 39-55. doi: 10.34172/apb.2021.005
PMID: 33747851        PMCID: PMC7961228

Review Article

Platelet Microparticle Controversial Role in Cancer

Mahnaz Nazari 1,2 ORCID, Ehsan Javandoost 3, Mehdi Talebi 1,4, Aliakbar Movassaghpour 1 * , Masoud Soleimani 3 * ORCID

Cited by CrossRef: 8


1- Nikravesh F, Mirzaee Khalilabadi R, Farsinejad A, Mardani Valandani H. Platelet microparticles influence gene expression and modulate biological activities of chronic myeloid leukemia cells (K562). Mol Biol Rep. 2024;51(1) [Crossref]
2- Alberro A, Iparraguirre L, Fernandes A, Otaegui D. Extracellular Vesicles in Blood: Sources, Effects, and Applications. IJMS. 2021;22(15):8163 [Crossref]
3- Dohle E, Zhu L, Sader R, Ghanaati S. Effect of Liquid Blood Concentrates on Cell Proliferation and Cell Cycle- and Apoptosis-Related Gene Expressions in Nonmelanoma Skin Cancer Cells: A Comparative In Vitro Study. IJMS. 2024;25(23):12983 [Crossref]
4- Zhang X, Yu S, Li X, Wen X, Liu S, Zu R, Ren H, Li T, Yang C, Luo H. Research progress on the interaction between oxidative stress and platelets: Another avenue for cancer?. Pharmacological Research. 2023;191:106777 [Crossref]
5- Yari F, Ashoub M, Amirizadeh N, Nikougoftar M, valandani H, Khalilabadi R. Differential Expression of the hTERT Gene in Umbilical Cord-Derived Mesenchymal Stem Cells Cocultured with B Cell Precursor Leukemia Cell Microparticles or CD41+/CD61+ Platelet Microparticles. Biochem Genet. 2024;62(4):2796 [Crossref]
6- Przygodzka P, Soboska K, Sochacka E, Pacholczyk M, Braun M, Kassassir H, Papiewska-Pająk I, Kielbik M, Boncela J. Neuromedin U secreted by colorectal cancer cells promotes a tumour-supporting microenvironment. Cell Commun Signal. 2022;20(1) [Crossref]
7- Anderson R, Rapoport B, Steel H, Theron A. Pro-Tumorigenic and Thrombotic Activities of Platelets in Lung Cancer. IJMS. 2023;24(15):11927 [Crossref]
8- Weiss L, Macleod H, Maguire P. Platelet-derived extracellular vesicles in cardiovascular disease and treatment – from maintaining homeostasis to targeted drug delivery. 2025;32(1):4 [Crossref]
9- Fortunato D, Giannoukakos S, Giménez-Capitán A, Hackenberg M, Molina-Vila M, Zarovni N. Selective isolation of extracellular vesicles from minimally processed human plasma as a translational strategy for liquid biopsies. Biomark Res. 2022;10(1) [Crossref]