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Adv Pharm Bull. 2021;11(2): 233-247. doi: 10.34172/apb.2021.029
PMID: 33880345        PMCID: PMC8046386

Review Article

Roles of miRNAs in Colorectal Cancer: Therapeutic Implications and Clinical Opportunities

Amir Mehrgou 1 ORCID, Shima Ebadollahi 2, Khaled Seidi 3, Mohammad Hosein Ayoubi-Joshaghani 4,5, Amirhossein Ahmadieh Yazdi 6, Peyman Zare 7,8, Mehdi Jaymand 9 * , Rana Jahanban-Esfahlan 10,11 *

Cited by CrossRef: 5


1- Farouk S, Elbrashy M, Moustafa R, El-Shenawy R, Helmy N, Khairy A, Bader El Din N. Unique dysregulation of miR-7, miR-15, and miR-203 as novel biomarkers in Egyptian colorectal cancer. Biomarkers in Medicine. 2025;19(20):999 [Crossref]
2- Pelisenco I, Trandafir B, Dobre A, Dragne A, Herlea V, Niculae A, Vasilescu C, Hinescu M, Milanesi E, Dobre M. MicroRNAs in colorectal cancer: A comparative analysis of circulating and tissue microRNA levels. World J Gastrointest Oncol. 2025;17(11) [Crossref]
3- Sharifi-Azad M, Fathi M, Cho W, Barzegari A, Dadashi H, Dadashpour M, Jahanban-Esfahlan R. Recent advances in targeted drug delivery systems for resistant colorectal cancer. Cancer Cell Int. 2022;22(1) [Crossref]
4- Kaveh Zenjanab M, Hashemzadeh N, Alimohammadvand S, Sharifi-Azad M, Dalir Abdolahinia E, Jahanban-Esfahlan R. Notch Signaling Suppression by Golden Phytochemicals: Potential for Cancer Therapy. Adv Pharm Bull. 2024;14(2):302 [Crossref]
5- Hasan M, Bakheet M, Ali H, Al-Saedi M, Mohammed M. Dual Role of miR-150 in Colorectal Cancer Progression: A Quantitative Real-Time PCR Study. Al-Rafidain J Med Sci. 2025;8(1):221 [Crossref]
6- Fawzy M, Hassan H, Sedky N, Nafie M, Youness R, Fahmy S. Revolutionizing cancer therapy: nanoformulation of miRNA-34 – enhancing delivery and efficacy for various cancer immunotherapies: a review. Nanoscale Adv. 2024;6(21):5220 [Crossref]
7- Niemira M, Bielska A, Chwialkowska K, Raczkowska J, Skwarska A, Erol A, Zeller A, Sokolowska G, Toczydlowski D, Sidorkiewicz I, Mariak Z, Reszec J, Lyson T, Moniuszko M, Kretowski A. Circulating serum miR-362-3p and miR-6721-5p as potential biomarkers for classification patients with adult-type diffuse glioma. Front Mol Biosci. 2024;11 [Crossref]
8- Muthu R, Manickam R, Thamarai R, Sivasamy S, Mahendran K, Prabhakaran R. NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation. Front Genet. 2025;16 [Crossref]