Time to Change Theory; Medical Leech from a Molecular Medicine Perspective Leech Salivary Proteins Playing a Potential Role in Medicine

Amir Shakouri ¹ * , Uwe Wollina ²

Cited by CrossRef: 7

1- Shakouri A, Kahroba H, Hamishekar H, Abdolalizadeh J. Nanoencapsulation of Hirudo medicinalis proteins in liposomes as a nanocarrier for inhibiting angiogenesis through targeting VEGFA in the Breast cancer cell line (MCF-7). Bioimpacts. 2021;12(2):115 [Crossref]

2- Witwit L. Cytotoxic effect of silver nanoparticles biosynthesized from Hirudo medicinalis saliva on HepG2 cells. Rev Clin Pharmacol Pharmacokinet, Int Ed. 2024;38(Sup2):177 [Crossref]

3- Ceylan M, Çetinkaya O, Bulut C. Acute Toxicity of Zinc on Southern Medicinal Leech, Hirudo verbana Carena, 1820. 2021;17(3):421 [Crossref]

4- Ghazzay M, Al-Hilli E. The Medical Benefits of Medicinal Leeches. ijbea. 2024;3(3):212 [Crossref]

5- Marquez-Gil K, Mesa E, Kouka N, Fonarov I, Casadesus D. Medicinal Leeches to Aid in Post-procedural Hematoma Evacuation. 2023; [Crossref]

6- Sun Y, Cheng G, Du L, Gan Y, Li B, Yan S, Shao M, Jin H, Li S. Chuanzhitongluo capsule ameliorates microcirculatory dysfunction in rats: Efficacy evaluation and metabolic profiles. Front Pharmacol. 2022;13 [Crossref]

7- Turlaev M, Shikhnebiev A, Kardanova Z, Rokhoev M, Mutigullina K, Zakiev R, Baklanova O, Baklanov I. Socio-Economic Aspects of the Development of Hirudotherapy in Russia. Entomol Appl Sci Lett. 2022;9(4):79 [Crossref]

8- Tural Ö, Ayhan H. The Anti-Proliferative Activity of Lyophilised Medicinal Leech (Hirudo Verbana) Saliva Extract on Breast Cancer Cell Line (MCF-7). 2024; [Crossref]