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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Adv Pharm Bull. 2022;12(3): 568-582. doi: 10.34172/apb.2022.060
PMID: 35935046        PMCID: PMC9348528

Research Article

5FU-loaded PCL/Chitosan/Fe3O4 Core-Shell Nanofibers Structure: An Approach to Multi-Mode Anticancer System

Mehdi Hadjianfar 1 * ORCID, Dariush Semnani 1 ORCID, Jaleh Varshosaz 2 ORCID, Sajad Mohammadi 3, Sayed Pedram Rezazadeh Tehrani 1

Cited by CrossRef: 13

1- Xie S, Zhang J, Orf C, Byars A, Zhu M. Stimuli‐Responsive Core‐Shell Electrospun Nanofibers for Drug Delivery: A Mini‐Review. J of Applied Polymer Sci. 2025;142(17) [Crossref]
2- Kaur M, Sharma A, Puri V, Aggarwal G, Maman P, Huanbutta K, Nagpal M, Sangnim T. Chitosan-Based Polymer Blends for Drug Delivery Systems. Polymers. 2023;15(9):2028 [Crossref]
3- Tayebi-Khorrami V, Rahmanian-Devin P, Fadaei M, Movaffagh J, Askari V. Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters. International Journal of Pharmaceutics: X. 2024;8:100265 [Crossref]
4- Alabrahim O, Azzazy H. Synergistic anticancer effect of Pistacia lentiscus essential oils and 5-Fluorouracil co-loaded onto biodegradable nanofibers against melanoma and breast cancer. Discover Nano. 2024;19(1) [Crossref]
5- Jaisankar E, Azarudeen R, Thirumarimurugan M. Nanofibers Embedded with Nanoparticles as Carriers for the Controlled Release of Anticancer Drug: Promoting the Apoptosis of Breast Cancer Cell Line and Growth Inhibition of Microbial Strains. ACS Appl Bio Mater. 2024;7(7):4323 [Crossref]
6- Taokaew S, Chuenkaek T. Developments of Core/Shell Chitosan-Based Nanofibers by Electrospinning Techniques: A Review. Fibers. 2024;12(3):26 [Crossref]
7- Rekha K, Ezhil Vizhi R, Lahiri B, Philip J. Synthesis, physico-chemical properties, and AC induction heating of polycaprolactone-coated bio-compatible Fe3O4 nanoparticles. Inorganic Chemistry Communications. 2024;165:112466 [Crossref]
8- Rakhshani A, Maghsoudian S, Ejarestaghi N, Yousefi M, Yoosefi S, Asadzadeh N, Fatahi Y, Darbasizadeh B, Nouri Z, Bahadorikhalili S, Shaabani A, Farhadnejad H, Motasadizadeh H. Polyethylene oxide-chitosan-doxorubicin/polycaprolactone-chitosan-curcumin pH-sensitive core/shell nanofibrous mats for the treatment of breast cancer: Fabrication, characterization and in vitro and in vivo evaluation. International Journal of Biological Macromolecules. 2025;305:141191 [Crossref]
9- Ercelik M, Tekin C, Parin F, Mutlu B, Dogan H, Tezcan G, Aksoy S, Gurbuz M, Yildirim K, Bekar A, Kocaeli H, Taskapilioglu M, Eser P, Tunca B. Co-loading of Temozolomide with Oleuropein or rutin into polylactic acid core-shell nanofiber webs inhibit glioblastoma cell by controlled release. International Journal of Biological Macromolecules. 2023;253:126722 [Crossref]
10- Nasari M, Semnani D, Amanpour S. Manufacturing and characterizing of the poly (ε-caprolactone)/poly (N-vinyl-2-pyrrolidone) core-shell nanofibers loaded by multi-walled carbon nanotubes coated by polypyrrole via vapor phase and chemical method and its application as an electro-responsive anticancer drug delivery system. International Journal of Polymeric Materials and Polymeric Biomaterials. 2023;72(13):1009 [Crossref]
11- Devi S, Giri J, Makki E, Suryavanshi M. Navigating the novel nanoparticles: current insights, innovations, and future vistas in detection and treatment of cervical cancer. Nanocomposites. 2024;10(1):256 [Crossref]
12- Cordoba A, Guernelli M, Montalti M, Saldías C, Focarete M, Leiva A. Nanofibers of chitosan-polycaprolactone blends as active support for photocatalytic nanoparticles: Outstanding role of chitosan in the degradation of an organic dye in water. International Journal of Biological Macromolecules. 2023;253:127111 [Crossref]
13- Huner K, Sarac B, Yüce E, Rezvan A, Micusik M, Omastova M, Eckert J, Sarac A. Iron oxide – poly(m-anthranilic acid)–poly(ε-caprolactone) electrospun composite nanofibers: fabrication and properties. Mol Syst Des Eng. 2023;8(3):394 [Crossref]
14- Saadh M, Hsu C, Mustafa M, Mutee A, Kaur I, Ghildiyal P, Ali A, Adil M, Ali M, Alsaikhan F, Narmani A, Farhood B. Advances in chitosan-based blends as potential drug delivery systems: A review. International Journal of Biological Macromolecules. 2024;273:132916 [Crossref]
15- Noori F, Bozorgi A, Farmani A, Abbasi A, Ai J, Tavassoli A, Ghasemian A, Morovvati H, Alipanah H, Ataollahi M, Ebrahimi L, Kouhpayeh S, Goodarzi A. Fabrication and in Vivo Evaluation of Hybrid Squalene-Loaded Nanofiber Scaffolds Based on Poly(ε-Caprolactone)/Polyvinyl Alcohol/Chitosan for Wound Healing Applications. J Polym Environ. 2025;33(5):2515 [Crossref]