Design and Development of Antibacterial/Anti-inflammatory Dual Drug-Loaded Nanofibrous Inserts for Ophthalmic Sustained Delivery of Gentamicin and Methylprednisolone: In Vitro Bioassay, Solvent, and Method Effects’ Evaluation

Shahla Mirzaeei ^1,2 * , Donya Barfar ^3,4

Cited by CrossRef: 11

1- Zuhour M, Güneş C, Fındık S, Dündar M, Gök O, Altuntaş Z. Effect of methylprednisolone loaded poly lactic-co-glycolic acid (PLGA) bioabsorbable nanofibers on tendon healing and adhesion formation. Journal of Drug Delivery Science and Technology. 2023;89:104988 [Crossref]

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3- Omer S, Zelkó R. A Systematic Review of Drug-Loaded Electrospun Nanofiber-Based Ophthalmic Inserts. Pharmaceutics. 2021;13(10):1637 [Crossref]

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6- Taghe S, Mirzaeei S, Hosseinkhani T. Design and development of dual drug-loaded nanofibrous inserts for ophthalmic sustained delivery of AMK and VAN: Pharmacokinetic study in rabbit’s eye. International Journal of Pharmaceutics. 2024;656:124056 [Crossref]

7- Taghe S, Mirzaeei S, Pakdaman N, Kazemi A, Nokhodchi A. Macrolide-loaded nanofibrous inserts with polycaprolactone and cellulose acetate base for sustained ocular delivery: Pharmacokinetic study in Rabbit’s eye. International Journal of Pharmaceutics. 2024;665:124699 [Crossref]

8- Chiang M, Chern E. More than Antibiotics: Latest Therapeutics in the Treatment and Prevention of Ocular Surface Infections. JCM. 2022;11(14):4195 [Crossref]

9- Gunduz O, Ulag S. Gentamicin and fluconazole loaded electrospun polymethylmethacrylate (PMMA) fibers as a novel platform for the treatment of corneal keratitis. International Journal of Polymeric Materials and Polymeric Biomaterials. 2023;72(12):995 [Crossref]

10- Sahu D, Rath G, Gupta G. Addressing ocular drug delivery challenges with solid nanofiber variants and supramolecular nanofibrous gel composite. Journal of Drug Delivery Science and Technology. 2024;94:105476 [Crossref]