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Adv Pharm Bull. 2022;12(3): 583-592. doi: 10.34172/apb.2022.061

PMID: 35935041 PMCID: PMC9348535

Research Article

Implementation of a Design of Experiments to Improve Periplasmic Yield of Functional ScFv Antibodies in a Phage Display Platform

Marjan Abri Aghdam ¹ , Mohammad Reza Tohidkia ² * , Elham Ghamghami ¹, Asadollah Ahmadikhah ³, Morteza Khanmahamadi ⁴, Behzad Baradaran ⁵, Ahad Mokhtarzadeh ⁵ *

Cited by CrossRef: 2

1- Guimarães M, Luz D, Pires Augusto E, Vieira L, Costa M, Fontes Piazza R, da Cruz Pradella J. Cost-effective production process of scFv antibody fragments against Shiga toxin 2 via recombinant E. coli. Current Research in Biotechnology. 2025;10:100310 [Crossref]

2- de Souza C, Glória J, da Silva E, de Lima Guerra Corado A, de Alcântara K, Cordeiro I, de Andrade E, Mariúba L. Single-Stranded Variable Fragment Gene Libraries Built for Phage Display: An Updated Review of Design, Selection and Application. J Microbiol Biotechnol. 2024;35 [Crossref]

3- Mani S, Arab B, Akbari V, Chou C. Integrated bioprocessing and genetic strategies to enhance soluble expression of anti-HER2 immunotoxin in E. Coli. AMB Expr. 2024;14(1) [Crossref]