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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Adv Pharm Bull. 2023;13(2): 218-232. doi: 10.34172/apb.2023.028
PMID: 37342386        PMCID: PMC10278216

Review Article

Polymersomes Based Versatile Nanoplatforms for Controlled Drug Delivery and Imaging

Rohini Kotha 1, Divya Dhatri Kara 1 ORCID, Rajeshwari Roychowdhury 2, Katikala Tanvi 2, Mahalaxmi Rathnanand 1 * ORCID

Cited by CrossRef: 8

1- Hu J, Arvejeh P, Bone S, Hett E, Marincola F, Roh K. Nanocarriers for cutting-edge cancer immunotherapies. J Transl Med. 2025;23(1) [Crossref]
2- Liu L, Chen Y, Lu D. Overview of Recent Advances in Nano-Based Ocular Drug Delivery. IJMS. 2023;24(20):15352 [Crossref]
3- Salatin S, Farhoudi M, Sadigh-Eteghad S, Mahmoudi J. Magnetic hybrid nanovesicles for the precise diagnosis and treatment of central nervous system disorders. Expert Opinion on Drug Delivery. 2024;21(4):521 [Crossref]
4- Cheng Y, Qu Z, Jiang Q, Xu T, Zheng H, Ye P, He M, Tong Y, Ma Y, Bao A. Functional Materials for Subcellular Targeting Strategies in Cancer Therapy: Progress and Prospects. Advanced Materials. 2025;37(31) [Crossref]
5- Cazzaniga G, Mori M, Griego A, Scarpa E, Moschetti G, Muzzioli S, Stelitano G, Chiarelli L, Cocorullo M, Casali E, Porta A, Zanoni G, Tresoldi A, Pini E, Batalha Í, Battaglia G, Tuccinardi T, Rizzello L, Villa S, Meneghetti F. Nanoenabling MbtI Inhibitors for Next-Generation Tuberculosis Therapy. J Med Chem. 2025;68(5):5312 [Crossref]
6- Hassan S, Ayaz A, Nawaz A, Khalil S, Maqsood S, Athar S, Rasheed A, Saeed S, Shams S, Sultan H. Smart Nanocarriers as an Emerging Platform in Urologic Cancer Immunotherapy: A Review on Clinical Insights and Applications. J Urol Oncol. 2025;23(2):164 [Crossref]
7- Soleymani S, Naghib S, Mozafari M. pH/ Temperature/ Redox and Light-responsive Polymersome Structure and Application in Cancer Therapy: Smart Drug Delivery and Targeted Drug Release. CMC. 2025;32(22):4456 [Crossref]
8- Garifo S, Vangijzegem T, Stanicki D, Laurent S. A Review on the Design of Carbon-Based Nanomaterials as MRI Contrast Agents. Molecules. 2024;29(7):1639 [Crossref]
9- Goel S, Singh R, Tonk M. Polymersomes as Next Generation Nanocarriers for Drug Delivery: Recent Advances, Patents, Synthesis and Characterization. CNANO. 2024;20(6):753 [Crossref]
10- Teo M, Loo H, Goh B, Chuah L. Progress in topical nanoformulations against bacterial skin and soft tissue infections– current trends. Drug Deliv and Transl Res. 2025; [Crossref]
11- Katamesh A, Abdel-Bar H, Mahafdeh R, Bin Break M, Hassoun S, Subaiea G, El-Naggar M, Almansour K, Abo El-Enin H, Yassin H. Tunable Intranasal Polymersome Nanocarriers Triggered Olanzapine Brain Delivery and Improved In Vivo Antipsychotic Activity. Pharmaceutics. 2025;17(7):811 [Crossref]
12- Fonseca M, Jarak I, Victor F, Domingues C, Veiga F, Figueiras A. Polymersomes as the Next Attractive Generation of Drug Delivery Systems: Definition, Synthesis and Applications. Materials. 2024;17(2):319 [Crossref]
13- Fu X, Yue T, Ren B, Wang H, Ren W, Lu X. A Powerful Strategy for Synthesizing Block Copolymers via Bimetallic Synergistic Catalysis. Angew Chem Int Ed. 2024;63(18) [Crossref]
14- Yetisgin A, Sivakumar P, Cetinel S. Current state and potential of polymersomes as ocular drug delivery systems. Nanoscale. 2025;17(24):14458 [Crossref]
15- Salatin S, Azarfarin M, Farjami A, Hamidi S. The simultaneous use of nanovesicles and magnetic nanoparticles for cancer targeting and imaging. Therapeutic Delivery. 2025;16(2):167 [Crossref]
16- Cetin F, Cernochova Z, Vermeersch E, Herynek V, Groborz O, Pavlova E, Slouf M, Hruby M, Mignon A, Hoogenboom R, Vlierberghe S, Kolouchova K. Dual thermo- and ROS-responsive triblock copolymers as 19F MRI tracers for functional nanoparticles and hydrogels. European Polymer Journal. 2025;238:114211 [Crossref]
17- Lai W. Design and Applications of Polymersomes for Oral Drug Administration. ACS Appl Mater Interfaces. 2025;17(21):30423 [Crossref]
18- Chakraborty R, Kannan S, Afrose N, Narayanasamy D. Tumor microenvironment expressed enzymes (Matrix metalloproteinases, cathepsins, urokinase-type plasminogen activator) triggered polymersomes for liquid biopsy and cancer diagnostics: A review. International Journal of Biological Macromolecules. 2025;321:146375 [Crossref]
19- Ivanova N. Local Chemotherapy of Skin Pre-Neoplastic Lesions and Malignancies from the Perspective of Current Pharmaceutics. Pharmaceutics. 2025;17(8):1009 [Crossref]
20- Cetin F, Mignon A, Van Vlierberghe S, Kolouchova K. Polymer‐ and Lipid‐Based Nanostructures Serving Wound Healing Applications: A Review. Adv Healthcare Materials. 2025;14(1) [Crossref]
21- Fu X, Yue T, Ren B, Wang H, Ren W, Lu X. A Powerful Strategy for Synthesizing Block Copolymers via Bimetallic Synergistic Catalysis. Angewandte Chemie. 2024;136(18) [Crossref]