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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Adv Pharm Bull. 2023;13(2): 275-282. doi: 10.34172/apb.2023.030
PMID: 37342385        PMCID: PMC10278227

Mini Review

Chitosan and Its Structural Modifications for siRNA Delivery

Mona Y. Al-Absi 1 ORCID, Anna Eleonora Caprifico 1 ORCID, Gianpiero Calabrese 1 * ORCID

Cited by CrossRef: 8

1- Karayianni M, Sentoukas T, Skandalis A, Pippa N, Pispas S. Chitosan-Based Nanoparticles for Nucleic Acid Delivery: Technological Aspects, Applications, and Future Perspectives. Pharmaceutics. 2023;15(7):1849 [Crossref]
2- Singh P, Singh M, Singh B, Sharma K, Kumar N, Singh D, Klair H, Mastana S. Implications of siRNA Therapy in Bone Health: Silencing Communicates. Biomedicines. 2024;12(1):90 [Crossref]
3- Antoniou V, Mourelatou E, Galatou E, Avgoustakis K, Hatziantoniou S. Gene Therapy with Chitosan Nanoparticles: Modern Formulation Strategies for Enhancing Cancer Cell Transfection. Pharmaceutics. 2024;16(7):868 [Crossref]
4- Redhwan M, M.G. H, Samaddar S, Bafail D, Hard S, Guha S. Chitosan/siRNA nanoparticles targeting PARP-1 attenuate Neuroinflammation and apoptosis in hyperglycemia-induced oxidative stress in Neuro2a cells. International Journal of Biological Macromolecules. 2024;282:136964 [Crossref]
5- Kögel D, Temme A, Aigner A. Recent advances in development and delivery of non-viral nucleic acid therapeutics for brain tumor therapy. Pharmacology & Therapeutics. 2025;266:108762 [Crossref]
6- Wang Z, Pang S, Liu X, Dong Z, Tian Y, Ashrafizadeh M, Rabiee N, Ertas Y, Mao Y. Chitosan- and hyaluronic acid-based nanoarchitectures in phototherapy: Combination cancer chemotherapy, immunotherapy and gene therapy. International Journal of Biological Macromolecules. 2024;273:132579 [Crossref]
7- Yao Z, Liu T, Wang J, Fu Y, Zhao J, Wang X, Li Y, Yang X, He Z. Targeted delivery systems of siRNA based on ionizable lipid nanoparticles and cationic polymer vectors. Biotechnology Advances. 2025;81:108546 [Crossref]
8- Regev A, Benafsha C, Goldbart R, Traitel T, Elkabets M, Kost J. Effect of Degree of Substitution and Molecular Weight on Transfection Efficacy of Starch-Based siRNA Delivery System. Polysaccharides. 2024;5(4):580 [Crossref]