Logo-apb
Adv Pharm Bull. 2023;13(3): 446-460. doi: 10.34172/apb.2023.056
PMID: 37646052        PMCID: PMC10460807

Review Article

An Overview of Nanostructured Lipid Carriers and its Application in Drug Delivery through Different Routes

Shadab Khan 1 * ORCID, Ajay Sharma 1, Vikas Jain 1 * ORCID

Cited by CrossRef: 25


1- Karim N, Shishir M, Marappan G, Khan S, Hashim S, Aalim H, Arslan M, Tahir H, Zhihua L, Zhai X, Rahman M, Tangpong J, Zou X. Recent advances in delivering mangosteen-based phytochemicals using promising micro/nanocarriers: Formulation, outcomes, and perspectives. Trends in Food Science & Technology. 2024;153:104734 [Crossref]
2- Dzyhovskyi V, Romani A, Pula W, Bondi A, Ferrara F, Melloni E, Gonelli A, Pozza E, Voltan R, Sguizzato M, Secchiero P, Esposito E. Characterization Methods for Nanoparticle–Skin Interactions: An Overview. Life. 2024;14(5):599 [Crossref]
3- Araújo G, Loureiro A, Rodrigues J, Barros P, Halicki P, Ramos D, Marinho M, Vaiss D, Vaz G, Yurgel V, Bidone J, Muccillo-Baisch A, Hort M, Paulo A, Dora C. Toward a Platform for the Treatment of Burns: An Assessment of Nanoemulsions vs. Nanostructured Lipid Carriers Loaded with Curcumin. Biomedicines. 2023;11(12):3348 [Crossref]
4- Brouillard M, Mathieu T, Guillot S, Méducin F, Roy V, Marcheteau E, Gallardo F, Caire-Maurisier F, Favetta P, Agrofoglio L. Lyotropic liquid crystal emulsions of LAVR-289: Influence of internal mesophase structure on cytotoxicity and in-vitro antiviral activity. International Journal of Pharmaceutics. 2024;665:124683 [Crossref]
5- Baig M, Karade S, Ahmad A, Khan M, Haque A, Webster T, Faiyazuddin M, Al-Qahtani N. Lipid-based nanoparticles: innovations in ocular drug delivery. Front Mol Biosci. 2024;11 [Crossref]
6- Sawatphakdee G, Yostawonkul J, Oontawee S, Rodprasert W, Sawangmake C, Kornsuthisopon C, Yata T, Tabtieang S, Nowwarote N, Pirarat N. Feasibility of Nanostructured Lipid Carrier Loaded with Alpha-Mangostin and Clove Oil for Canine Periodontal Therapy. Animals. 2024;14(14):2084 [Crossref]
7- Heydari S, Barzegar-Jalali M, Heydari M, Radmehr A, Paiva-Santos A, Kouhsoltani M, Hamishehkar H. The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration. Bioimpacts. 2024;14(6):30243 [Crossref]
8- Cocoș F, Anuța V, Popa L, Ghica M, Nica M, Mihăilă M, Fierăscu R, Trică B, Nicolae C, Dinu-Pîrvu C. Development and Evaluation of Docetaxel-Loaded Nanostructured Lipid Carriers for Skin Cancer Therapy. Pharmaceutics. 2024;16(7):960 [Crossref]
9- Tarannum N, Pooja K, Jakhar S, Mavi A. Nanoparticles assisted intra and transdermic delivery of antifungal ointment: an updated review. Discover Nano. 2024;19(1) [Crossref]
10- Das M, Sarma A, Baruah H, Basak D. Insight into central nervous system targeted nanostructured lipid carriers via the nose to brain pathway. RSC Pharm. 2024; [Crossref]
11- Costa J, Costa A, Azevedo-Silva J, Tavares-Valente D, Sousa S, Neto T, Pintado M, Madureira A. Silica Microparticles from Sugarcane By-Products as an Encapsulation System for Retinoids Aimed at Topical Sustained Release. IJMS. 2024;25(6):3215 [Crossref]
12- Haque M, Shrestha A, Mikelis C, Mattheolabakis G. Comprehensive analysis of lipid nanoparticle formulation and preparation for RNA delivery. International Journal of Pharmaceutics: X. 2024;8:100283 [Crossref]
13- Toma L, Deleanu M, Sanda G, Barbălată T, Niculescu L, Sima A, Stancu C. Bioactive Compounds Formulated in Phytosomes Administered as Complementary Therapy for Metabolic Disorders. IJMS. 2024;25(8):4162 [Crossref]
14- Peira E, Sapino S, Chirio D, Chindamo G, Riganti C, Godel M, Chegaev K, Gallarate M. Development of targeted lipid nanoparticles for the combined therapy of triple negative breast cancer: can curcumin and 6-aminoflavone promote doxorubicin in vitro efficacy?. Journal of Drug Delivery Science and Technology. 2024;:106414 [Crossref]
15- Shehata T, Aldhubiab B, Elsewedy H. Virgin Coconut Oil-based Nanostructured Lipid Carrier Improves the Hypolipidemic Effect of Rosuvastatin. IJN. 2024;Volume 19:7945 [Crossref]
16- Pawar V, Dessai A, Nayak U. Oleogels: Versatile Novel Semi-Solid System for Pharmaceuticals. AAPS PharmSciTech. 2024;25(6) [Crossref]
17- Sarkar P, Sardar M, Sen O, Das S, Manna S. Therapeutic Efficacy of Nanocarrier‐Mediated Inhalable Gene Transfection for Lung Cancer. ChemistrySelect. 2024;9(37) [Crossref]
18- Susa F, Arpicco S, Pirri C, Limongi T. An Overview on the Physiopathology of the Blood–Brain Barrier and the Lipid-Based Nanocarriers for Central Nervous System Delivery. Pharmaceutics. 2024;16(7):849 [Crossref]
19- Salgaonkar S, Purewal J, Doshi G, Fernandes T, Gharat S, Sawarkar S. New Insights in Psoriasis Management using Herbal Drug Nanocarriers. CPD. 2024;30(32):2550 [Crossref]
20- Wang H, Bo W, Feng X, Zhang J, Li G, Chen Y. Strategies and Recent Advances on Improving Efficient Antitumor of Lenvatinib Based on Nanoparticle Delivery System. IJN. 2024;Volume 19:5581 [Crossref]
21- Noor L, Hafeez A, Rahman M, Vishwakarma K, Kapoor A, Ara N, Aqeel R. Demystifying the Potential of Embelin-Loaded Nanoformulations: a Comprehensive Review. AAPS PharmSciTech. 2024;25(8) [Crossref]
22- Mohammadi J, Ebrahimi S, Ghodousi M, Mahmoodi M, Hheidari A, Pishbin E, Kharaba Z, Rahdar A, Romanholo Ferreira L. Genetic-bioengineering of nanotechnology in cell-specific pharmaceutical targeting: Biological, pharmacological, and biochemical impact of nanomaterials-based breast cancer therapies. Journal of Drug Delivery Science and Technology. 2024;101:106249 [Crossref]
23- Zheng B, Pan F, Shi M, He C, He B, Wang R, Ren G, Yang S, Zhang S. 2-Monoacylglycerol Mimetic Liposomes to Promote Intestinal Lymphatic Transport for Improving Oral Bioavailability of Dihydroartemisinin. IJN. 2024;Volume 19:5273 [Crossref]
24- Fathi F, Machado T, de A. C. Kodel H, Portugal I, Ferreira I, Zielinska A, Oliveira M, Souto E. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the delivery of bioactives sourced from plants: part I – composition and production methods. Expert Opinion on Drug Delivery. 2024;21(10):1479 [Crossref]
25- Jin S, Sung J. Delivery Strategies of siRNA Therapeutics for Hair Loss Therapy. IJMS. 2024;25(14):7612 [Crossref]
26- Kumbhar P, Kolekar K, Nadaf S, Vishwas S, Kamble V, Bhagwat D, Gupta G, Deshannavar U, Singh S, Dua K, Disouza J, Patravale V. Expanding the arsenal against diabetes mellitus via transdermal application of drug-loaded nanoparticles and microneedles: Recent advances and future perspectives. Journal of Drug Delivery Science and Technology. 2024;98:105930 [Crossref]
27- Rauf S, Ahmed N, Fatima S, Khan D, Rehman A, Rehman A. Aceclofenac Delivery through Polymeric Nanoparticles loaded with Transdermal Hydrogel against Rheumatoid Arthritis. Journal of Drug Delivery Science and Technology. 2024;:106419 [Crossref]
28- Alfutaimani A, Alharbi N, Alahmari A, Alqabbani A, Aldayel A. Exploring the landscape of Lipid Nanoparticles (LNPs): A comprehensive review of LNPs types and biological sources of lipids. International Journal of Pharmaceutics: X. 2024;:100305 [Crossref]
29- Hasanpour F, Budai-Szűcs M, Kovács A, Ambrus R, Jójárt-Laczkovich O, Cseh M, Geretovszky Z, Ayaydin F, Berkó S. Improvement of lidocaine skin permeation by using passive and active enhancer methods. International Journal of Pharmaceutics. 2024;660:124377 [Crossref]
30- Aldhubiab B, Almuqbil R, Shehata T, Soliman W, Elsewedy H. Nanotechnological prospective for enhancing the antibacterial activity of mupirocin and cinnamon essential oil: a combination therapy. Front Pharmacol. 2024;15 [Crossref]
31- Gao X, Ciura K, Ma Y, Mikolajczyk A, Jagiello K, Wan Y, Gao Y, Zheng J, Zhong S, Puzyn T, Gao X. Toward the Integration of Machine Learning and Molecular Modeling for Designing Drug Delivery Nanocarriers. Advanced Materials. 2024;36(45) [Crossref]