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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Adv Pharm Bull. 2023;13(4): 747-760. doi: 10.34172/apb.2023.077
PMID: 38022805        PMCID: PMC10676553

Research Article

Targeted Delivery of Pennyroyal via Methotrexate Functionalized PEGylated Nanostructured Lipid Carriers into Breast Cancer Cells; A Multiple Pathways Apoptosis Activator

Amin Mahoutforoush 1,2,3 ORCID, Leila Asadollahi 2 ORCID, Hamed Hamishehkar 2 * ORCID, Soheil Abbaspour-Ravasjani 2 * ORCID, Atefeh Solouk 3 ORCID, Masoumeh Haghbin Nazarpak 4 ORCID

Cited by CrossRef: 6

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2- Naseem N, Kushwaha P, Haider F. Leveraging nanostructured lipid carriers to enhance targeted delivery and efficacy in breast cancer therapy: a comprehensive review. Naunyn-Schmiedeberg's Arch Pharmacol. 2025;398(1):449 [Crossref]
3- Nam S, Bharti D, Seong H, Kim Y, Jeong C, Yang K. Nanoemulsification of epigallocatechin gallate for debitterization, antibrowning, and inhibition of intracellular lipid accumulation. Food Bioscience. 2024;61:104792 [Crossref]
4- Medina-Magariño E, Pinos-Rodríguez J, Pulido-Capiz Á, García-González V, Torres-Maravilla E, Quiroz-Mercado J, Cano-Sarmiento C. Anti-proliferative and Pro-apoptotic Activity of a Novel Oil-in-Water Nanoemulsion Containing Tea Tree Oil, Quercetin, and Rosmarinic Acid in Breast Cancer Cells. BioNanoSci. 2025;15(1) [Crossref]
5- Rani S, Gupta S, Tejavath K, Gupta U. Effect of combination of polyphenols, polysaccharide, and sodium selenite on bortezomib anti-cancer action. International Journal of Biological Macromolecules. 2025;289:138809 [Crossref]
6- Asghariazar V, Vahidian F, Karimi A, Abbaspour-Ravasjani S, Mansoori B, Safarzadeh E, Laranjo M. The Role of Oleuropein, Derived from Olives, in Human Skin Fibroblast Cells: Investigating the Underlying Molecular Mechanisms of Cytotoxicity and Antioxidant and Anti‐Inflammatory Activities. International Journal of Clinical Practice. 2024;2024(1) [Crossref]
7- Bostiog D, Simionescu N, Coroaba A, Marinas I, Chifiriuc M, Gradisteanu Pircalabioru G, Maier S, Pinteala M. Multi-shell gold nanoparticles functionalized with methotrexate: a novel nanotherapeutic approach for improved antitumoral and antioxidant activity and enhanced biocompatibility. Drug Delivery. 2024;31(1) [Crossref]
8- Yang T, Liu Z, Zhang T, Liu Y. Hybrid nano-stimulator for specific amplification of oxidative stress and precise tumour treatment. Journal of Drug Targeting. 2024;32(7):756 [Crossref]
9- Wu D, Zhou B, Liu Y, Zhu X, Li B, Liang H. Tailoring carrier-free nanoparticles based on natural small molecule assembly for synergistic anti-tumor efficacy. Asian Journal of Pharmaceutical Sciences. 2025;20(1):100992 [Crossref]
10- Zhao Y, Yuan C, Shi Y, Liu X, Luo L, Zhang L, Pešić M, Yao H, Li L. Drug screening approaches for small-molecule compounds in cancer-targeted therapy. Journal of Drug Targeting. 2025;33(3):368 [Crossref]