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Adv Pharm Bull. 2024;14(2): 302-313. doi: 10.34172/apb.2024.035

PMID: 39206407 PMCID: PMC11347744

Review Article

Notch Signaling Suppression by Golden Phytochemicals: Potential for Cancer Therapy

Masoumeh Kaveh Zenjanab ¹ , Nastaran Hashemzadeh ², Sajjad Alimohammadvand ³, Masoumeh Sharifi-Azad ³, Elaheh Dalir Abdolahinia ⁴ * , Rana Jahanban-Esfahlan ^1,3 *

Cited by CrossRef: 2

1- Sah A, Das J, Umarovich A, Agarwal S, Prabhakar P, Vashishtha A, Elshaikh R, Choudhary R, Alfeel A. Targeting Cancer Stem Cells with Phytochemicals: Molecular Mechanisms and Therapeutic Potential. Biomedicines. 2026;14(1):215 [Crossref]

2- Hossain M, Wazed M, Asha S, Amin M, Shimul I. Dietary Phytochemicals in Health and Disease: Mechanisms, Clinical Evidence, and Applications—A Comprehensive Review. Food Science & Nutrition. 2025;13(3) [Crossref]

3- Sharifi-Azad M, Kaveh Zenjanab M, Shahpouri M, Adili-Aghdam M, Fathi M, Jahanban-Esfahlan R. Codelivery of methotrexate and silibinin by niosome nanoparticles for enhanced chemotherapy of CT26 colon cancer cells. Biomed Mater. 2024;19(5):055015 [Crossref]

4- Hooshiar M, Khalaf Ansar B, Shaghaghian R, Banavand M, Sharif S, Zamani K, Esfahlan R. Curcumin and Silibinin loaded pegylated nanoniosome for cancer therapy: bioinformatics and in vitro study. Mol Biol Rep. 2025;52(1) [Crossref]

5- Melrose J. The Potential of Bioactive Plant Phytochemicals, Pro-Resolving Anti-Inflammatory Lipids, and Statins in the Inhibition of Intervertebral Disc Degeneration, Low Back Pain Resolution, Disc Functional Repair, and Promotion of Intervertebral Disc Regeneration. Cells. 2025;14(22):1758 [Crossref]

6- Faraji-Barhagh A, Jahandar-Lashaki S, Esfahlan R, Alizadeh E. Current nano drug delivery systems for targeting head and neck squamous cell carcinoma microenvironment: a narrative review. Mol Biol Rep. 2025;52(1) [Crossref]

7- Nie R, Luo H, Liu Y, Wang S, Hou Y, Chen C, Wang H, Lv H, Tao X, Jing Z, Zhang H, Li P. Notch signaling pathway modulation by food functional ingredients: mechanisms, cancer and immunoregulation. Front Cell Dev Biol. 2026;13 [Crossref]

8- Kaveh Zenjanab M, Alimohammadvand S, Doustmihan A, Kianian S, Sadeghzadeh Oskouei B, Mazloomi M, Akbari M, Jahanban-Esfahlan R. Paclitaxel for breast cancer therapy: A review on effective drug combination modalities and nano drug delivery platforms. Journal of Drug Delivery Science and Technology. 2024;95:105567 [Crossref]