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Adv Pharm Bull. 2024;14(3): 646-664. doi: 10.34172/apb.2024.057
PMID: 39494264        PMCID: PMC11530890

Research Article

Development of Gentamicin Bilosomes Laden In Situ Gel for Topical Ocular Delivery: Optimization, In Vitro Characterization, Toxicity, and Anti-microbial Evaluation

Ameeduzzafar Zafar 1 * ORCID, Omar Awad Alsaidan 1, Malik Suliman Mohamed 1, Mohd Yasir 2, Mohammad Khalid 3

Cited by CrossRef: 0


1- Afzal M, Ahmed N, Fatima S, Shah K, Shah A. Optimization and Evaluation of Compritol-Based Lipid-Polymer Hybrid Nanoparticles Loaded Transdermal Patch of Gentamicin Targeting Aerobic Bacteria. BioNanoSci. 2025;15(4) [Crossref]
2- Priya S, Desai V, Singh H, Taliyan R, Singhvi G. Enhancing 3-acetyl-11-keto-β-boswellic acid skin permeation via nanostructured lipid carriers: integrating quality by design principles for risk estimation and optimization. Nanoscale Adv. 2025;7(22):7285 [Crossref]
3- Ijaz F, Nasir B, Rashid S, Naseem F, Jalil A, Riaz A, Latip J, Alzahrani K, Alsharif K, Azad A. Colistin adorned topical nanoemulsion gel formulation for enhanced anti-microbial activity. Sci Rep. 2025;15(1) [Crossref]
4- Rajbhar N, Singhal D, Nijhawan H, Verma P, Soni G, Yadav K. Bilosomes as a novel ocular drug delivery system: Assessing the material attributes, process parameters, and quality attributes. Experimental Eye Research. 2025;255:110364 [Crossref]
5- Mohy K, Elhabak M, Elkasabgy N, Fahmy R, Younes N. Bilosomes-mediated trans-ocular delivery of azelastine hydrochloride for the treatment of allergic conjunctivitis: In vitro, ex vivo and in vivo investigations. Journal of Drug Delivery Science and Technology. 2026;115:107673 [Crossref]
6- Shelke M, Kolhe M, Ghogare R, Bhor R. Development and Evaluation of Daridorexant-Loaded pH-Sensitive In Situ Nasal Gel for Enhancing Bioavailability. BioNanoSci. 2025;15(4) [Crossref]