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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Adv Pharm Bull. 2024;14(3): 543-557. doi: 10.34172/apb.2024.059
PMID: 39494249        PMCID: PMC11530876

Review Article

Novel Advances in Cell-Free Therapy for Premature Ovarian Failure (POF): A Comprehensive Review

Yahya Yahyavi 1 ORCID, Niloufar Kheradi 2 ORCID, Abbas Karimi 1 ORCID, Abbas Ebrahimi-Kalan 3 ORCID, Fatemeh Ramezani 1 ORCID, Soudabe Yousefi 4 ORCID, Shirin Teymouri Nobari 5 ORCID, Hourieh Sadrekarimi 6 ORCID, Mohammad Nouri 4 * ORCID, Mahdi Edalati 7 * ORCID

Cited by CrossRef: 0

1- Guo Z, Kawamura K. Ovarian Function Restoration Using Autologous Platelet‐Rich Plasma. Reprod Medicine & Biology. 2025;24(1) [Crossref]
2- Yu S, Liu J, Chen S. Mapping the research landscape of exosomes in premature ovarian insufficiency: A bibliometric analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2026;321:115090 [Crossref]
3- Wang M, Chen H, Lin S, Meng Z, Zhang Y, Liu F, Li M, Sun C, Guan M, Song L, Zhao G, Zhang D, Qin J. Quercetin ameliorates cyclophosphamide-induced premature ovarian insufficiency by modulating SIRT1/HIF-1α pathway. J Ovarian Res. 2026;19(1) [Crossref]
4- Liu X, Feng C, Zhu T, Qin Z, Han Y, Wang Y, Li X, Suo Y. Aspartame triggers premature ovarian failure via SIRT1-dependent suppression of the PI3K/AKT/mTOR pathway and induction of oxidative stress and apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2027;1873(1):168425 [Crossref]
5- He S, Ling L, Sheng Y, Zhao X, Yuan L, Liu P, Li B, Zhang B. Bridging tradition and innovation: electroacupuncture’s impact on premature ovarian insufficiency. Front Endocrinol. 2026;16 [Crossref]
6- Sadeghi Y, Deda L, Albar M, Casper R. Granulocyte colony-stimulating factor treatment in women with premature ovarian insufficiency: a pilot clinical study of biological activity and menstrual resumption. Reprod Biol Endocrinol. 2026;24(1) [Crossref]
7- Ghasemi D, Ghahremani-Nasab M, Barzegari A, Khalili A, Del Bakhshayesh A. Cell-free regenerative therapies for female infertility: The emerging role of mesenchymal stem cell secretome. Tissue and Cell. 2026;102:103547 [Crossref]
8- Jia C, Li H, Ju R, Zhang P, Peng L, Xue T, Zhu X, Wang S, Luo J, Zhu R, Jing X, Cui X. Mechanisms of mitochondrial dysfunction in premature ovarian insufficiency. J Ovarian Res. 2026;19(1) [Crossref]