Adv Pharm Bull. 2019;9(3): 360-373.
doi: 10.15171/apb.2019.043
PMID: 31592054
PMCID: PMC6773933
Scopus ID: 85070479561
  Abstract View: 945
  PDF Download: 591

Review Article

The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip

Ali Alirezaie Alavijeh 1 ORCID logo, Mohammad Barati 2* ORCID logo, Meisam Barati 3 ORCID logo, Hussein Abbasi Dehkordi 1 ORCID logo

1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
2 Department of Applied Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
3 Student Research Committee, Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


Cancer is an abnormal cell growth which tends to proliferate in an uncontrolled way and, in some cases, leads to metastasis. If cancer is left untreated, it can immediately cause death. The use of magnetic nanoparticles (MNPs) as a drug delivery system will enable drugs to target tissues and cell types precisely. This study describes usual strategies and consideration for the synthesis of MNPs and incorporates payload drug on MNPs. They have advantages such as visual targeting and delivering which will be discussed in this review. In addition, we considered body magnetic field to make drug delivery process more effective and safer by the application of MNPs and tumor-on-chip.
Keywords: Body magnetic fields, Cancer, Drug delivery, Magnetic nanoparticles
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Submitted: 17 Dec 2018
Revision: 18 May 2019
Accepted: 20 May 2019
ePublished: 01 Aug 2019
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