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2026, Vol 16, No. 2

Advanced Pharmaceutical Bulletin (APB) is a peer-reviewed multidisciplinary open access journal, covering a wide range of integrative fields within Pharmaceutical sciences.
APB is the official journal of Drug Applied Research Center and Faculty of Pharmacy, published by TUOMS PRESS, Tabriz University of Medical Sciences.

Why Publish with APB?

Free of charge publication for all article types
Fast and constructive peer review
Simple and efficient online submission
Author-friendly review process
Rapid publication by means of running issue concept, which gives authors the benefit of 'No Waiting Time' for the officially accepted manuscripts
Free publication of color images
Worldwide visibility of papers (Open Access Journal)

Original Research

1. Chaperone-Assisted Soluble Expression of a Humanized Anti-EGFR ScFv Antibody in E. Coli

Kamal Veisi, Safar Farajnia*, Nosratollah Zarghami, Hamid Reza Khoram Khorshid, Nasser Samadi, Shiva Ahdi Khosroshahi, Hossein Zarei Jaliani

Adv Pharm Bull. 2015;5(5): 621-627. doi: 10.15171/apb.2015.084

PMCID: PMC4708032 PMID: 26793607 Scopus ID: 84954104894

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Original Research

2. Synthesis of PCEC Copolymers with Controlled Molecular Weight Using Full Factorial Methodology

Leila Barghi, Davoud Asgari, Jaleh Barar, Hadi Valizadeh*

Adv Pharm Bull. 2015;5(1): 51-56. doi: 10.5681/apb.2015.007

PMCID: PMC4352223 PMID: 25789219 Scopus ID: 84924624339

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Review Article

3. The Challenges of Recombinant Endostatin in Clinical Application: Focus on the Different Expression Systems and Molecular Bioengineering

Abbas Mohajeri, Sarvin Sanaei, Farhad Kiafar, Amir Fattahi, Majid Khalili, Nosratollah Zarghami*

Adv Pharm Bull. 2017;7(1): 21-34. doi: 10.15171/apb.2017.004

PMCID: PMC5426730 PMID: 28507934 Scopus ID: 85017542839

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Research Article

4. In Silico Exploration of Aryl Halides Analogues as CheckpointKinase 1 Inhibitors by Using 3D QSAR, Molecular Docking Study,and ADMET Screening

Adib Ghaleb* , Adnane Aouidate , Mohammed Bouachrine , Tahar Lakhlifi , Abdelouhid Sbai

Adv Pharm Bull. 2019;9(1): 84-92. doi: 10.15171/apb.2019.011

PMCID: PMC6468235 PMID: 31011562 Scopus ID: 85066137698

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Short Communication

5. Study of Thermal Analysis Behavior of Fenbendazole and Rafoxanide

Ali Kamal Attia*, Ahmed Sayed Saad, Manal Sami Alaraki, Eman Saad Elzanfaly

Adv Pharm Bull. 2017;7(2): 329-334. doi: 10.15171/apb.2017.039

PMCID: PMC5527248 PMID: 28761836 Scopus ID: 85021456264

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Research Article

6. Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation

Omid Zarei, Maryam Hamzeh-Mivehroud*, Silvia Benvenuti, Fulya Ustun-Alkan, Siavoush Dastmalchi*

Adv Pharm Bull. 2017;7(1): 141-150. doi: 10.15171/apb.2017.018

PMCID: PMC5426727 PMID: 28507948 Scopus ID: 85017566787

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Short Communication

7. A Molecular Study on Drug Delivery System Based on Carbon Nanotube Compared to Silicon Carbide Nanotube for Encapsulation of Platinum-Based Anticancer Drug

Zahra Khatti, Seyed Majid Hashemianzadeh, Seyed Ali Shafiei*

Adv Pharm Bull. 2018;8(1): 163-167. doi: 10.15171/apb.2018.020

PMCID: PMC5896391 PMID: 29670852 Scopus ID: 85044078032

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Research Article

8. Molecular Identification and Probiotic Potential Characterization of Lactic Acid Bacteria Isolated from Human Vaginal Microbiota

Yousef Nami* , Babak Haghshenas, Ahmad Yari Khosroushahi

Adv Pharm Bull. 2018;8(4): 683-695. doi: 10.15171/apb.2018.077

PMCID: PMC6311637 PMID: 30607341 Scopus ID: 85057756466

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Research Article

9. Identification of Novel Mutations in Arabidopsis thaliana DOF 4.2 Coding Gene

Omid Jamshidi Kandjani , Mahdieh Rahbar-Shahrouziasl, Ali Akbar Alizadeh, Maryam Hamzeh-Mivehroud, Siavoush Dastmalchi*

Adv Pharm Bull. 2021;11(3): 557-563. doi: 10.34172/apb.2021.064

PMCID: PMC8421617 PMID: 34513631 Scopus ID: 85108916709

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Research Article

10. Studying the Effect of Amino Acid Substitutions in the M2 Ion Channel of the Influenza Virus on the Antiviral Activity of the Aminoadamantane Derivative In Vitro and In Silico

Timur Mansurovich Garaev* , Artyom Irorevich Odnovorov , Alexander Aleksandrovich Lashkov , Tatiana Vladimirovna Grebennikova , Marina Pavlovna Finogenova , Galina Kadymovna Sadykova , Alexei Gennadievich Prilipov , Tatiana Anatol'evna Timofeeva, Sergey Vadimovich Rubinsky, Svetlana Nikolaevna Norkina, Marina Mikhailovna Zhuravleva

Adv Pharm Bull. 2021;11(4): 700-711. doi: 10.34172/apb.2021.079

PMCID: PMC8642805 PMID: 34888217 Scopus ID: 85117178199

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Original Research

11. Thermal Analysis Investigation of Dapoxetine and Vardenafil Hydrochlorides using Molecular Orbital Calculations

Ali Kamal Attia*, Eglal R. Souaya, Ethar A. Soliman

Adv Pharm Bull. 2015;5(4): 523-529. doi: 10.15171/apb.2015.071

PMCID: PMC4729354 PMID: 26819925 Scopus ID: 84949668205

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Review Article

12. Coenzyme Q10 and Its Therapeutic Potencies Against COVID-19 and Other Similar Infections: A Molecular Review

Mohammad Fakhrolmobasheri , Mahnaz-Sadat Hosseini, Seyedeh-Ghazal Shahrokh, Zahra Mohammadi, Mohammad-Javad Kahlani, Seyed-Erfan Majidi, Mehrdad Zeinalian*

Adv Pharm Bull. 2023;13(2): 233-243. doi: 10.34172/apb.2023.026

PMCID: PMC10278218 PMID: 37342382

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Research Article

13. Molecular Docking and Preclinical Study of Five-Membered S,S-Palladaheterocycle as Hepatoprotective Agent

Nail Salavatovich Akhmadiev , Albina Midkhatovna Galimova, Vnira Rakhimovna Akhmetova* , Veronika Radievna Khairullina, Rozaliia Akramovna Galimova, Eduard Feliksovich Agletdinov, Askhat Gabdrahmanovich Ibragimov , Valery Alekseevich Kataev

Adv Pharm Bull. 2019;9(4): 674-684. doi: 10.15171/apb.2019.079

PMCID: PMC6912183 PMID: 31857974 Scopus ID: 85075837479

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Review Article

14. Translocator Protein 18 kDa (TSPO): A Promising Molecular Target for Image-Guided Surgery of Solid Cancers

Hendris Wongso* , Ahmad Kurniawan, Yanuar Setiadi, Crhisterra E. Kusumaningrum, Eva M. Widyasari, Teguh H.A. Wibawa, Isa Mahendra, Muhamad B. Febrian, Maula E. Sriyani, Iim Halimah, Isti Daruwati, Rudi Gunawan, Arifudin Achmad, Dwianto H. Nugraha, Ronny Lesmana, Ari S. Nugraha

Adv Pharm Bull. 2024;14(1): 86-104. doi: 10.34172/apb.2024.015

PMCID: PMC10997928 PMID: 38585455

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Research Article

15. Effects of Resveratrol on the Structure and Catalytic Function of Bovine Liver catalase (BLC): Spectroscopic and Theoretical Studies

Samaneh Rashtbari, Gholamreza Dehghan*, Reza Yekta, Abolghasem Jouyban, Mehrdad Iranshahi

Adv Pharm Bull. 2017;7(3): 349-357. doi: 10.15171/apb.2017.042

PMCID: PMC5651055 PMID: 29071216 Scopus ID: 85030117458

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Original Article

16. Apigenin as a Multi-Targeted Agent in Gastrointestinal Cancers: A Systems Pharmacology Approach

Duaa Kamel Al-Moussawi, Aseel Kamil Mohammed Al-Mosawi, Awatif Mokar Dayesh, Mohammad Hosseinzadeh Hesari* , Hamid Cheshomi*

Adv Pharm Bull. 2026;16(1): 74-90. doi: 10.34172/apb.025.45970

PMCID: PMC13408527 PMID: 42524089

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Research Article

17. The Comparison Between the Mutated HuIFN-β 27-101 and the Wild Type Interferon β: the Comprehensive In Silico Study to Evaluate the Effect of Mutations on IFN-β

Sayed Sharif Balkhi , Zohreh Hojati*

Adv Pharm Bull. 2019;9(4): 640-648. doi: 10.15171/apb.2019.074

PMCID: PMC6912172 PMID: 31857969 Scopus ID: 85075826162

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Mini Review

18. Next-Generation Targeted Molecular Therapies in Immune-Mediated Inflammatory Diseases

Mostafa Akbarzadeh-Khiavi , Amir-Hossein Olfati, Azam Safary*

Adv Pharm Bull. 2026;16(2): 332-342. doi: 10.34172/apb.46844

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Research Article

19. Drug Repurposing for Identification of S1P1 Agonists with Potential Application in Multiple Sclerosis Using In Silico Drug Design Approaches

Ali Akbar Alizadeh , Behzad Jafari, Siavoush Dastmalchi*

Adv Pharm Bull. 2023;13(1): 113-122. doi: 10.34172/apb.2023.012

PMCID: PMC9871275 PMID: 36721815

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Original Article

20. Design and Evaluation of a Chalcone-Based Dimeric Scaffold Targeting Amyloid-Beta Plaques for Early Detection of Alzheimer’s Disease: Synthesis, Radiolabeling, In Vivo Studies, and Integrated Molecular Docking and Dynamics Simulation

Zahra Ghiamaty , Mehdi Akhlaghi* , Safura Jokar* , Hooman Hafezi, Omid Bavi, Mohammad Sharifzadeh, Omid Sabzevari, Mehdi Shafiee Ardestani, Tahereh Ghorbandaeipour, Mahboobeh Asadi, Mahshid Kiani, Sara Roustaei, Fatemeh Ebrahimi, Davood Beiki*

Adv Pharm Bull. 2026;16(2): 416-431. doi: 10.34172/apb.46659

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Research Article

21. New Prospective Phosphodiesterase Inhibitors: Phosphorylated Oxazole Derivatives in Treatment of Hypertension

Iryna V. Nizhenkovska , Kateryna V. Matskevych* , Oksana I. Golovchenko , Oleksandr V. Golovchenko , Antonina D. Kustovska , Mikhaeel Van

Adv Pharm Bull. 2023;13(2): 399-407. doi: 10.34172/apb.2023.044

PMCID: PMC10278226 PMID: 37342374

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Research Article

22. CEP55 Inhibitor: Extensive Computational Approach Defining a New Target of Cell Cycle Machinery Agent

Beni Lestari , Rohmad Yudi Utomo*

Adv Pharm Bull. 2022;12(1): 191-199. doi: 10.34172/apb.2022.021

PMCID: PMC9012919 PMID: 35517890 Scopus ID: 85127174885

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